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Uterine Cancer

Source: MedlinePlus Health Topics, U.S. National Library of Medicine

Last synced 8/7/2026Status: primary verified

What is uterine cancer? Uterine cancer is a cancer that forms in tissues of the uterus , which is sometimes called the womb. The uterus is the place where a fetus grows during pregnancy. There are two types of uterine cancer: Endometrial cancer is the most common type. This type of cancer begins in the cells lining the uterus, known as the endometrium. Uterine sarcoma is a rare, more aggressive cancer that is harder to treat. This type of cancer begins in muscle or other tissues in the uterus. Who is more likely to develop uterine cancer? Uterine cancer usually happens after menopause. The cause is unknown. However, some factors and conditions that change the balance of hormones in your body may increase your risk. These can include obesity or metabolic syndrome (a group of risk factors for certain health problems). Other factors and conditions that may increase your risk for: Endometrial cancer Taking estrogen-only hormone therapy after menopause. Having type 2 diabetes Starting menstruation at an early age or menopause at a later age Having never been pregnant Taking tamoxifen, a medicine used to prevent or treat breast cancer Having polycystic ovary syndrome Having a mother, sister, or daughter who has had endometrial cancer Having certain genetic conditions, such as Lynch syndrome Having endometrial hyperplasia (thickening of the uterine lining) Uterine sarcoma Having had past treatment with radiation therapy to the pelvis Taking tamoxifen, a medicine used to prevent or treat breast cancer What are the symptoms of uterine cancer? The most common symptom of both endometrial cancer and uterine sarcoma is abnormal vaginal bleeding . Both types of uterine cancer may also cause pelvic pain or pressure, unusual vaginal discharge, or an enlarged uterus or pelvic mass. Less common symptoms may include urinating (peeing) often, having trouble urinating, or pain during sexual intercourse. How is uterine cancer diagnosed? If you have symptoms of uterine cancer, your health

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This information is for general education and is not medical advice. Always talk to a licensed U.S. clinician about your situation, medications, or treatment decisions.