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The Effect ofMouthwash on Halitosis and Oral Hygiene in Orthodontic Patients: A Randomized Clinical Trial.

Source: PubMed, NCBI / U.S. National Library of Medicine

Dentistry journalGranika Angeliki, Karamesinis Konstantinos, Mylonopoulou Ioulia-Maria, et al.Published 5/4/2026Last synced 5/30/2026Status: syncedPMID: 42187644DOI: 10.3390/dj14050266

: This study evaluated the effectiveness of(Smoke Tree) Flower Water mouthwash in reducing halitosis and improving oral hygiene parameters among adolescents undergoing fixed orthodontic treatment.: A double-blind, randomized, placebo-controlled, parallel-group clinical trial was conducted with 30 individuals undergoing treatment with fixed orthodontic appliances. Participants were allocated (1:1) into two groups: Group A received themouthwash, while Group B received the placebo mouthwash. Hydrogen sulfide (HS) concentration in breath, measured by the OralChromaII device, was the primary outcome. Secondary outcomes included dimethyl sulfide [(CH)S] and methyl mercaptan (CHSH) levels, assessed with the same device, and oral hygiene status evaluated using the Modified Silness & L&#xf6;e Plaque (PI-M) as well as the Silness & L&#xf6;e Gingival (GI) indices. Normality of the data distribution was assessed using the Shapiro-Wilk test. Statistical analyses were conducted using the Mann-Whitney U test and Student's-test.: A statistically significant reduction in HS levels was observed in thegroup compared to placebo (= 0.014). Median HS levels decreased from 147.00 ppb at baseline (T0) to 35.00 ppb at follow-up (T1) after 2 weeks. A statistically significant reduction in total VSC levels was also observed in thegroup compared to placebo (< 0.001). Median total VSC levels decreased from 254.00 ppb at baseline (T0) to 105.00 ppb at follow-up (T1) after 2 weeks. No significant differenc

Abstract

: This study evaluated the effectiveness of(Smoke Tree) Flower Water mouthwash in reducing halitosis and improving oral hygiene parameters among adolescents undergoing fixed orthodontic treatment.: A double-blind, randomized, placebo-controlled, parallel-group clinical trial was conducted with 30 individuals undergoing treatment with fixed orthodontic appliances. Participants were allocated (1:1) into two groups: Group A received themouthwash, while Group B received the placebo mouthwash. Hydrogen sulfide (HS) concentration in breath, measured by the OralChromaII device, was the primary outcome. Secondary outcomes included dimethyl sulfide [(CH)S] and methyl mercaptan (CHSH) levels, assessed with the same device, and oral hygiene status evaluated using the Modified Silness & L&#xf6;e Plaque (PI-M) as well as the Silness & L&#xf6;e Gingival (GI) indices. Normality of the data distribution was assessed using the Shapiro-Wilk test. Statistical analyses were conducted using the Mann-Whitney U test and Student's-test.: A statistically significant reduction in HS levels was observed in thegroup compared to placebo (= 0.014). Median HS levels decreased from 147.00 ppb at baseline (T0) to 35.00 ppb at follow-up (T1) after 2 weeks. A statistically significant reduction in total VSC levels was also observed in thegroup compared to placebo (< 0.001). Median total VSC levels decreased from 254.00 ppb at baseline (T0) to 105.00 ppb at follow-up (T1) after 2 weeks. No significant differences were found between groups for the other volatile sulfur compounds. A Significant improvements were noted in periodontal parameters in favor of thegroup. The Gingival Index decreased from 2.0 to 1.3 (< 0.001; 95% CI: -0.7 to -0.2), and the Plaque Index (PI-M) decreased from 1.6 to 1.0 (= 0.001; 95% CI: -0.7 to -0.3).:mouthwash appeared to be an effective adjunct for managing halitosis and improving oral hygiene parameters in adolescents undergoing fixed orthodontic treatment. No adverse effects were reported.

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