Tested but unprotected? Uncovering missed opportunities in hepatitis B prevention among health professionals in Sierra Leone

Abstract

Introduction Hepatitis B virus (HBV) remains a major occupational hazard for healthcare workers (HCWs), particularly in low-resource settings like Sierra Leone, where systemic challenges hinder effective prevention efforts. Despite the availability of an effective vaccine since 1982 and widespread screening initiatives, HBV vaccination uptake among HCWs remains alarmingly low. This study investigates the disconnect between HBV screening and subsequent vaccination among HCWs in Sierra Leone, examining individual, institutional, and systemic factors. st1 Methods we employed a mixed-methods cross-sectional design. A total of 432 HCWs were sampled across public, private, NGO, and faith-based hospitals using multi-stage techniques to assess screening uptake, vaccination coverage, and influencing factors. Additionally, 12 in-depth interviews were conducted with senior staff and health administrators. Quantitative data were analysed using SPSS, while the qualitative data were thematically analysed. st2 Results quantitative findings revealed suboptimal levels of HBV vaccination and screening among HCWs. Overall, - 65% of HCWs were screened for HBV, while 52% received at least one vaccine dose, and only 34% completed the full three-dose series. Nearly half of those screened were not vaccinated, exposing critical failures in follow-up care. Screening and vaccination rates varied by cadre. Higher uptake was observed among administrators (100.0%), doctors (88.2%), community health officers (68.8%), other clinical staff (68.8%), and laboratory technicians (54.2%). In contrast, nurses (43.4%), pharmacists (34.9%), and other essential staff (13.2%) reported lower coverage levels. Differences were also noted across facility types. Private facilities recorded the highest screening (77.3%) and vaccination (62.5%) rates, followed by NGOs (70.8% and 66.7%). Faith-based facilities recorded moderate levels (56.4% screening and 54.5% vaccination), while public facilities had 64.4% screening but relatively the lowest 44.7% vaccination coverage. Screening and vaccination uptake were significantly associated (Χ= 317.27, p < 0.05). st3 Conclusion the findings underscore critical missed opportunities in HBV prevention among HCWs in Sierra Leone. Despite moderate screening rates, vaccine coverage remains low, primarily due to institutional weaknesses such as inadequate follow-up systems, limited vaccine access, and weak policy enforcement - rather than individual neglect. These gaps place frontline health professionals at continued risk of HBV infection. Strengthening HBV prevention requires integrated screening-vaccination programs, mandatory occupational health policies, and sustainable vaccine supply systems. Targeted education, consistent advocacy, and inclusive strategies that engage all healthcare worker cadres are also vital. Such interventions are essential not only for protecting the healthcare workforce but also for reinforcing public health resilience in Sierra Leone. st4