Prevalence of Getah Virus in Mammals in East and Southeast Asia: A Systematic Review and Meta‐Analysis

Source: PubMed Central Open Access, NCBI / U.S. National Library of Medicine

Getah virus (GETV) has reemerged as an important mosquito‐borne pathogen affecting livestock health in East and Southeast Asia. To quantify its epidemiological patterns, we conducted a Preferred Reporting Items for Systematic Reviews and Meta‐Analyses (PRISMA)‐compliant meta‐analysis of literature published between 2000 and September 2025. Analysis of 24 observational studies covering swine, equine, bovine, caprine, and wildlife populations using a random‐effects model revealed a pooled mammalian seroprevalence of 26% (95% confidence interval [CI]: 0.17–0.38) and a pooled nucleic acid positivity rate of 2% (95% CI: 0.01–0.05), consistent with broad past exposure but limited detection of active viremia in cross‐sectional surveys. Swine were identified as the main amplifying hosts, particularly in intensive farming regions of eastern and southern China, where herd seropositivity exceeded 60%. Results indicate a significant prevalence increase over the past 25 years. The established mosquito–swine–mosquito transmission cycle confirms GETV has transformed from a sporadic pathogen into a persistent threat within intensive farming environments.