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Metabolic Syndrome

Source: MedlinePlus Health Topics, U.S. National Library of Medicine

Last synced 8/4/2026Status: primary verified

What is metabolic syndrome? Metabolic syndrome is the name for a group of risk factors for heart disease , diabetes , and other health problems. You can have just one risk factor, but people often have several of them together. When you have at least three of them, it is called metabolic syndrome. These risk factors include: A large waistline, also called abdominal obesity or "having an apple shape." Too much fat around the stomach is a greater risk factor for heart disease than too much fat in other parts of the body. Having a high triglyceride level. Triglycerides are a type of fat found in the blood. Having a low HDL cholesterol level . HDL is sometimes called the "good" cholesterol because it helps remove cholesterol from your arteries. Having high blood pressure . If your blood pressure stays high over time, it can damage your heart and lead to other health problems. Having a high fasting blood sugar . Mildly high blood sugar may be an early sign of diabetes. The more factors you have, the higher your risk for heart disease, diabetes, and stroke is. What causes metabolic syndrome? Metabolic syndrome has several causes that act together: Overweight and obesity An inactive lifestyle Insulin resistance, a condition in which the body can't use insulin properly. Insulin is a hormone that helps move blood sugar into your cells to give them energy. Insulin resistance can lead to high blood sugar levels. Age - your risk goes up as get older Genetics - ethnicity and family history People who have metabolic syndrome often also have excessive blood clotting and inflammation throughout the body. Researchers don't know whether these conditions cause metabolic syndrome or worsen it. Who is at risk for metabolic syndrome? The most important risk factors for metabolic syndrome are: Abdominal obesity (a large waistline) An inactive lifestyle Insulin resistance There are certain groups of people who have an increased risk of metabolic syndrome: Some racial and ethnic groups. Mex

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This information is for general education and is not medical advice. Always talk to a licensed U.S. clinician about your situation, medications, or treatment decisions.