Kaposi Sarcoma

Source: MedlinePlus Health Topics, U.S. National Library of Medicine

Last synced 8/15/2026Status: primary verified

What is Kaposi sarcoma? Kaposi sarcoma, sometimes called KS, is a type of cancer. It causes lesions (abnormal tissue) to grow in different parts of the body, including: The skin Lymph nodes Mucous membranes (the lining of the mouth, nose, and throat) Other organs These lesions are usually red or purple. They are made of cancer cells, new blood vessels, and blood cells. The lesions may begin in more than one place in the body at the same time. This makes Kaposi sarcoma different from other cancers. What causes Kaposi sarcoma and who is more likely to develop it? Kaposi sarcoma is caused by infection with human herpesvirus-8 (HHV-8). This virus is also called Kaposi sarcoma-associated herpesvirus (KSHV). Most people infected with this virus don't get Kaposi sarcoma. But certain people who get this virus are more likely to develop one of the types of Kaposi sarcoma: People with weakened immune systems due to HIV can develop epidemic (HIV-associated) Kaposi sarcoma. People with weakened immune systems due to medicines they need to take after an organ transplant can develop iatrogenic (transplant-related) Kaposi sarcoma. Older men of Mediterranean or Eastern European Jewish heritage can develop classic Kaposi sarcoma. Young men in Africa can develop endemic (African) Kaposi sarcoma. What are the symptoms of Kaposi sarcoma? Kaposi sarcoma usually starts out as one or more red, purple, or brown skin lesions on the legs and feet. They are most often on the ankles or soles of the feet. Over time, lesions may form in other parts of the body. The lesions may not cause symptoms. But sometimes the lesions can cause problems, especially as you get more of them and they grow bigger. For example: Pressure from the lesions may block the flow of lymph and blood in the legs and cause painful swelling If lesions grow in your stomach or intestines, they can bleed and may cause abdominal (belly) pain and diarrhea Lesions in the lungs can also bleed and may cause shortness of breath How i

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This information is for general education and is not medical advice. Always talk to a licensed U.S. clinician about your situation, medications, or treatment decisions.