in Korean pig farms: antimicrobial resistance and toxin profiles.

Source: PubMed, NCBI / U.S. National Library of Medicine

is associated with neonatal piglet diarrhea and economic loss; contemporary national data on toxin gene carriage and antimicrobial susceptibility in Korea are limited. To characterize toxin gene profiles and antimicrobial resistance amongisolated from diarrheic piglets in Korea. Fecal samples (n = 1,627) were collected from 286 farms in 2023-2024.isolates (n = 410) were recovered under anaerobic conditions. Toxin genes (,,,,, and) were detected by multiplex real-time polymerase chain reaction. Susceptibility to 18 antimicrobials was assessed by disc diffusion. Type A strains (alone [24.6%] or+[46.8%]) predominated;andwere detected in 73.4% and 19.0% of isolates, respectively. Resistance was highest to bacitracin (94.9%), amoxicillin/clavulanic acid (79.8%), and florfenicol (81.5%). In 2023-2024, type A isolates carryingwere the predominant toxinotype amongrecovered from diarrheic piglets in Korea. The high prevalence of resistance to several commonly used agents supports strengthened antimicrobial stewardship and evaluation of alternative control strategies.