Library
PubMed
research article
Professional

Expanding Access to Cervical Cancer Screening for Transgender and Nonbinary Individuals.

Source: PubMed, NCBI / U.S. National Library of Medicine

Obstetrics and gynecology clinics of North AmericaMurphy Emma Chew, Rowen Tami SPublished 6/1/2026Last synced 6/4/2026Status: syncedPMID: 42236073DOI: 10.1016/j.ogc.2026.01.005

Cervical cancer screening for transgender and nonbinary (TNB) people should be offered in accordance with guidelines for cisgender women. Testosterone therapy has been associated with higher odds of inadequate cervical cytology and benign cervical changes, which may be difficult to differentiate from high-grade dysplasia. Patients with testosterone-related atrophy may benefit from pretreatment with topical estrogen. Growing data support self-collected HPV as an acceptable method for screening among TNB individuals for whom pelvic examination poses a barrier.

Educational only
This information is for general education and is not medical advice. Always talk to a licensed U.S. clinician about your situation, medications, or treatment decisions.