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Esophageal Bleeding and Radiational Esophagitis Presenting as Acute Gastroesophageal Junction Obstruction

Source: PubMed Central Open Access, NCBI / U.S. National Library of Medicine

Gastro Hep AdvancesLast synced 8/9/2026Status: syncedPMID: 42569128 pmidDOI: 10.1016/j.gastha.2026.101044

Acute gastroesophageal junction obstruction is an uncommon condition that can raise concern for malignancy. We report a case of spontaneous esophageal bleeding of a patient on chronic anticoagulation who received radiation therapy 4 months prior, presenting with sudden-onset intractable nausea, vomiting, and abdominal pain. Imaging demonstrated marked esophageal dilation with distal obstruction. Endoscopy revealed a large friable, near-obstructing esophageal mass with extensive clot burden. Repeated biopsies showed necrotic debris, inflammation, and fungal elements without malignancy. Endoscopic removal led to complete symptom resolution. abs0010

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