Duodenal Gastrointestinal Stromal Tumor Causing Gastrointestinal Bleeding and Duodenal Obstruction in Third-Trimester Pregnancy Successfully Treated with Pancreaticoduodenectomy after Emergency Cesarean Section: A Case Report.

Source: PubMed, NCBI / U.S. National Library of Medicine

We report a case of a pregnant woman suffering from gastrointestinal bleeding and duodenal obstruction caused by a gastrointestinal stromal tumor (GIST) that required pancreaticoduodenectomy after an emergent cesarean section. A pregnant woman at 37 weeks of gestation presented with vomiting and melena and was found to have severe anemia. Imaging revealed an 8-cm tumor in the pancreatic head associated with duodenal stenosis. She underwent an emergency cesarean section, resulting in the delivery of a healthy infant. Subtotal stomach-preserving pancreatoduodenectomy was performed 7 days after delivery. Histopathological findings confirmed the tumor as a GIST. Her lactation support was provided by a lactation consultant starting on POD 1. The postoperative course was uneventful, and the patient was discharged on POD 10. This case highlights the importance of flexible treatment decision-making based on maternal condition and tumor-related complications, together with multidisciplinary perinatal support in patients requiring major surgery shortly after delivery to minimize the duration of mother-infant separation.