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Combined therapeutic strategy of balloon pulmonary angioplasty before and after pulmonary endarterectomy in a patient with severe chronic thromboembolic pulmonary hypertension with Kartagener's syndrome: a case report.

Source: PubMed, NCBI / U.S. National Library of Medicine

European heart journal. Case reportsKasahara Tomohiro, Yamashita Jun, Komatsu Ikki, et al.Published 6/1/2026Last synced 6/14/2026Status: syncedPMID: 42273301DOI: 10.1093/ehjcr/ytaf349

This case report describes the novel use of balloon pulmonary angioplasty before and after pulmonary endarterectomy for treating severe chronic thromboembolic pulmonary hypertension in a patient with Kartagener's syndrome. Chronic thromboembolic pulmonary hypertension is recognized as one of the few treatable types of pulmonary hypertension, and pulmonary endarterectomy is the standard treatment. However, advanced age (e.g. >75 years) and certain comorbidities may make it difficult to perform pulmonary endarterectomy, and balloon pulmonary angioplasty and medical therapy can be alternative options in such cases. A 63-year-old woman with Kartagener's syndrome was diagnosed with severe chronic thromboembolic pulmonary hypertension after presenting with dyspnoea on exertion. She underwent preceding balloon pulmonary angioplasty without any complications to reduce the perioperative risk of pulmonary endarterectomy. An additional balloon pulmonary angioplasty after pulmonary endarterectomy was performed for residual dyspnoea, which led to improvement of the overall condition. Balloon pulmonary angioplasty before pulmonary endarterectomy may be indicated for high-risk cases for perioperative risk reduction. This report highlights the usefulness of the combination of balloon pulmonary angioplasty before and after pulmonary endarterectomy for the successful treatment of severe chronic thromboembolic pulmonary hypertension in a patient with Kartagener's syndrome, which may have variou

Abstract

This case report describes the novel use of balloon pulmonary angioplasty before and after pulmonary endarterectomy for treating severe chronic thromboembolic pulmonary hypertension in a patient with Kartagener's syndrome. Chronic thromboembolic pulmonary hypertension is recognized as one of the few treatable types of pulmonary hypertension, and pulmonary endarterectomy is the standard treatment. However, advanced age (e.g. >75 years) and certain comorbidities may make it difficult to perform pulmonary endarterectomy, and balloon pulmonary angioplasty and medical therapy can be alternative options in such cases. A 63-year-old woman with Kartagener's syndrome was diagnosed with severe chronic thromboembolic pulmonary hypertension after presenting with dyspnoea on exertion. She underwent preceding balloon pulmonary angioplasty without any complications to reduce the perioperative risk of pulmonary endarterectomy. An additional balloon pulmonary angioplasty after pulmonary endarterectomy was performed for residual dyspnoea, which led to improvement of the overall condition. Balloon pulmonary angioplasty before pulmonary endarterectomy may be indicated for high-risk cases for perioperative risk reduction. This report highlights the usefulness of the combination of balloon pulmonary angioplasty before and after pulmonary endarterectomy for the successful treatment of severe chronic thromboembolic pulmonary hypertension in a patient with Kartagener's syndrome, which may have various perioperative risks.

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