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Childhood Leukemia

Source: MedlinePlus Health Topics, U.S. National Library of Medicine

Last synced 8/10/2026Status: primary verified

What is leukemia? Leukemia is a term for cancers of the blood cells. Leukemia starts in blood-forming tissues such as the bone marrow. Your bone marrow makes the cells which will develop into white blood cells, red blood cells, and platelets. Each type of cell has a different job: White blood cells help your body fight infection Red blood cells deliver oxygen from your lungs to your tissues and organs Platelets help form clots to stop bleeding When you have leukemia, your bone marrow makes large numbers of abnormal cells. This problem most often happens with white blood cells. These abnormal cells build up in your bone marrow and blood. They crowd out the healthy blood cells and make it hard for your cells and blood to do their work. What are the types of leukemia in children? There are different types of leukemia. Some types are acute (fast growing). They usually get worse quickly if they are not treated. Most childhood leukemias are acute: Acute lymphocytic leukemia (ALL) , which is the most common type of leukemia in children and the most common cancer in children . In ALL, the bone marrow makes too many lymphocytes, a type of white blood cell. Acute myeloid leukemia (AML) , which happens when bone marrow makes abnormal myeloblasts (a type of white blood cell), red blood cells, or platelets. Other types of leukemia are chronic (slow growing). They usually get worse over a longer period of time. They are rare in children: Chronic lymphocytic leukemia (CLL), in which the bone marrow makes abnormal lymphocytes (a type of white blood cell). It is more common in teens than children. Chronic myeloid leukemia (CML), in which the bone marrow makes abnormal granulocytes (a type of white blood cell). It is very rare in children. There are some other rare types of leukemia in children, including juvenile myelomonocytic leukemia (JMML). What causes leukemia in children? Leukemia happens when there are changes in the genetic material (DNA) in bone marrow cells. The cause of t

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