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Amputation for Complex Regional Pain Syndrome Type 1

Source: PubMed Central Open Access, NCBI / U.S. National Library of Medicine

The Ochsner JournalLast synced 9/17/2026Status: syncedPMID: 42746659 pmidDOI: 10.31486/toj.25.0107

Background Complex regional pain syndrome (CRPS) is a chronic condition involving severe pain that can be resistant to many treatment modalities. Therapeutic amputation of the affected limb is unusual and controversial. Case Report A 33-year-old female with a 4-year history of CRPS associated with intractable foot and calf pain underwent elective transtibial amputation after conservative treatments failed. The patient's outcomes were favorable: resolution of pain and improved mobility sustained at 18 months postoperatively. Conclusion Amputation may be a viable last resort treatment option for selected patients with CRPS who are unresponsive to conventional treatments.

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