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Acute Lymphocytic Leukemia

Source: MedlinePlus Health Topics, U.S. National Library of Medicine

Last synced 8/9/2026Status: primary verified

What is leukemia? Leukemia is a term for cancers of the blood cells. Leukemia starts in blood-forming tissues such as the bone marrow. Your bone marrow makes the cells which will develop into white blood cells, red blood cells, and platelets. Each type of cell has a different job: White blood cells help your body fight infection Red blood cells deliver oxygen from your lungs to your tissues and organs Platelets help form clots to stop bleeding When you have leukemia, your bone marrow makes large numbers of abnormal cells. This problem most often happens with white blood cells. These abnormal cells build up in your bone marrow and blood. They crowd out the healthy blood cells and make it hard for your cells and blood to do their work. What is acute lymphocytic leukemia (ALL)? Acute lymphocytic leukemia is a type of acute leukemia. It's also called ALL and acute lymphoblastic leukemia. "Acute" means that it usually gets worse quickly if it's not treated. ALL is the most common type of cancer in children . It can also affect adults. In ALL, the bone marrow makes too many lymphocytes, a type of white blood cell. These cells normally help your body fight infection. But in ALL, they are abnormal and cannot fight infection very well. They also crowd out the healthy cells, which can lead to infection, anemia , and easy bleeding. These abnormal cells can also spread to other parts of the body, including the brain and spinal cord. What causes acute lymphocytic leukemia (ALL)? ALL happens when there are changes in the genetic material (DNA) in bone marrow cells. The cause of these genetic changes is unknown. However, there are certain factors that raise your risk of ALL. Who is at risk for acute lymphocytic leukemia (ALL)? The factors that raise your risk of ALL include: Being male Being white Being over age 70 Having had chemotherapy or radiation therapy Having been exposed to high levels of radiation Having certain genetic disorders , such as Down syndrome What are the sympt

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