A meta-analysis of bone conduction 80 Hz auditory steady-state response thresholds in adults and infants
Source: PubMed Central Open Access, NCBI / U.S. National Library of Medicine
Introduction Auditory steady-state responses (ASSRs) objectively estimate hearing thresholds in individuals unable to provide behavioral responses. Bone conduction (BC) testing differentiates conductive from sensorineural hearing loss. Accurate BC ASSR threshold estimation relies on correction values, which are not yet well established. The reliability of BC ASSR thresholds to estimate hearing thresholds at 500, 1,000, 2,000, and 4,000 Hz is evaluated. S1 Methods A systematic search was conducted to identify studies involving normal-hearing (NH) and hearing-impaired (HI) participants of all ages. Outcomes were (1) the difference between ASSR behavioral and ASSR thresholds, and (2) ASSR thresholds. The risk of bias was evaluated using the Newcastle-Ottawa Scale. The certainty of the evidence was assessed using GRADE approach. S2 Results Twelve records met the inclusion criteria, yielding a total of 29 studies. Sample sizes ranged from 60 to 271 participants across frequencies and age groups. Record quality ranged from low to high. Data were synthesized using random-effects models due to heterogeneity. In NH adults, the mean differences between BC ASSR thresholds and behavioral thresholds were 17.0, 15.5, 13.4, and 12.1 dB at 500, 1,000, 2,000, and 4,000 Hz, respectively. In NH infants, mean BC ASSR thresholds were 17.2, 10.5, 26.1, and 19.9 dB HL at the same frequencies. In infants with conductive HL, BC ASSR threshold was 20.3 at 500 Hz. The certainty of the evidence was very
Abstract
Introduction Auditory steady-state responses (ASSRs) objectively estimate hearing thresholds in individuals unable to provide behavioral responses. Bone conduction (BC) testing differentiates conductive from sensorineural hearing loss. Accurate BC ASSR threshold estimation relies on correction values, which are not yet well established. The reliability of BC ASSR thresholds to estimate hearing thresholds at 500, 1,000, 2,000, and 4,000 Hz is evaluated. S1 Methods A systematic search was conducted to identify studies involving normal-hearing (NH) and hearing-impaired (HI) participants of all ages. Outcomes were (1) the difference between ASSR behavioral and ASSR thresholds, and (2) ASSR thresholds. The risk of bias was evaluated using the Newcastle-Ottawa Scale. The certainty of the evidence was assessed using GRADE approach. S2 Results Twelve records met the inclusion criteria, yielding a total of 29 studies. Sample sizes ranged from 60 to 271 participants across frequencies and age groups. Record quality ranged from low to high. Data were synthesized using random-effects models due to heterogeneity. In NH adults, the mean differences between BC ASSR thresholds and behavioral thresholds were 17.0, 15.5, 13.4, and 12.1 dB at 500, 1,000, 2,000, and 4,000 Hz, respectively. In NH infants, mean BC ASSR thresholds were 17.2, 10.5, 26.1, and 19.9 dB HL at the same frequencies. In infants with conductive HL, BC ASSR threshold was 20.3 at 500 Hz. The certainty of the evidence was very low. S3 Conclusions Age and frequency impact BC ASSR thresholds, highlighting the need to develop correction values to accurately predict BC behavioral thresholds. . S4