A case of dental implant treatment for occlusal reconstruction in a congenital acute myeloid leukemia survivor.
Source: PubMed, NCBI / U.S. National Library of Medicine
The patient was an 11-year-old boy with a medical history of congenital acute myeloid leukemia (AML). He received a series of treatments between 1 and 8 months of age, including chemotherapy, total body irradiation, and peripheral blood stem cell transplantation. Although the permanent incisors had erupted, both crown and root formation were incomplete. No tooth buds were observed for the remaining permanent teeth. The deciduous teeth were still present; however, their roots were shortened and showed mobility. At 18 years of age, growth of the upper and lower jaws had ceased; therefore, occlusal rehabilitation was performed using implants. All teeth except the first molars were extracted, and six implants were placed in the jaws. A screw-retained, implant-supported bridge was fitted, and regular follow-up and maintenance were scheduled. Four years and 9 months after placement of the final prosthesis, the occlusion has remained stable. This patient had congenital AML and received chemotherapy during early childhood, coinciding with the critical period of tooth development and resulting in root shortening, tooth microdontia, and absence of tooth buds for the permanent teeth. Following completion of maxillofacial growth, occlusal rehabilitation was performed using implants, and the occlusion has remained stable. The findings of the present case suggest that implant-supported prosthetic treatment represents an effective option for full occlusal reconstruction in congenital AML su
Abstract
The patient was an 11-year-old boy with a medical history of congenital acute myeloid leukemia (AML). He received a series of treatments between 1 and 8 months of age, including chemotherapy, total body irradiation, and peripheral blood stem cell transplantation. Although the permanent incisors had erupted, both crown and root formation were incomplete. No tooth buds were observed for the remaining permanent teeth. The deciduous teeth were still present; however, their roots were shortened and showed mobility. At 18 years of age, growth of the upper and lower jaws had ceased; therefore, occlusal rehabilitation was performed using implants. All teeth except the first molars were extracted, and six implants were placed in the jaws. A screw-retained, implant-supported bridge was fitted, and regular follow-up and maintenance were scheduled. Four years and 9 months after placement of the final prosthesis, the occlusion has remained stable. This patient had congenital AML and received chemotherapy during early childhood, coinciding with the critical period of tooth development and resulting in root shortening, tooth microdontia, and absence of tooth buds for the permanent teeth. Following completion of maxillofacial growth, occlusal rehabilitation was performed using implants, and the occlusion has remained stable. The findings of the present case suggest that implant-supported prosthetic treatment represents an effective option for full occlusal reconstruction in congenital AML survivors with severe hypodontia. Dental implant treatment for full occlusal reconstruction in a patient with severe hypodontia who had received chemotherapy for AML is described herein.